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Pfizer and Arvinas Report Positive Trial Results for Breast Cancer Drug

Published 1 days agoPFE
Pfizer and Arvinas Report Positive Trial Results for Breast Cancer Drug

Pfizer and Arvinas have announced promising outcomes from their Phase 3 VERITAC-2 trial for vepdegestrant, an experimental breast cancer drug. The trial showed that vepdegestrant effectively delayed disease progression in patients with ESR1 gene mutations, surpassing AstraZeneca's Faslodex. Reuters highlighted that the median progression-free survival for these patients was five months with vepdegestrant, compared to just two months with Faslodex.


Additionally, in the broader patient population, vepdegestrant offered a slight improvement in median progression-free survival at 3.8 months, compared to 3.6 months with Faslodex. One key advantage of vepdegestrant noted in the trial is its oral administration, which offers greater convenience than Faslodex's intramuscular injection. Analysts forecast a potential peak in sales reaching $576 million by 2032.


Following these successful results, Pfizer and Arvinas are preparing to submit their findings to regulatory authorities worldwide, seeking approval for vepdegestrant. The oral convenience and efficacy of the drug mark a significant advance in treatment options for breast cancer patients, especially those with certain genetic mutations.

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